Job Description

At AstraZeneca, we work without barriers between functions at the cutting-edge of clinical science, it’s a place to rethink the future of medicine to answer some of the most complex unmet patient needs. That’s why we love it – this is the place to make a greater impact! We are now recruiting an Executive Director to lead our Clinical Innovation Team in the Translational Science & Experimental Medicine (TS&EM) department within Early Cardiovascular, Renal and Metabolism (CVRM) therapeutic area. In this role, you will have the opportunity to work at the forefront of translational science and early clinical research within CVRM. In a multidisciplinary and collaborative environment, you will play an important leadership role to promote the progression of a rich and diverse portfolio of investigational drugs in accordance with the TS&EM remit. The role may be located at one of AstraZeneca’s vibrant R&D sites in Cambridge (United Kingdom) Gaithersburg or Boston (USA) or Gothenburg (Sweden). Who We AreEarly CVRM is accountable for the discovery and development of new medicines within three main strategic disease areas - cardiovascular/heart failure, metabolism and chronic kidney disease. In the Early CVRM TS&EM Department we utilise data science, cutting edge laboratory methodology, well-phenotyped patient cohorts and innovative experimental medicine studies to accelerate the validation of drug targets in human disease; develop target-related biomarker strategies; generate precision medicine and/or patient segmentation hypotheses and establish the clinical line of sight & experimental medicine studies to support the development of investigational drugs within the rich Early CVRM portfolio. What you’ll doAs leader for the TS&EM Clinical Innovation Team, you will be responsible for overseeing design and delivery of clinical research activities that support human target validation, precision medicine and clinical line of sight for drug targets and investigational drugs in the Early CVRM portfolio. You will work in cross-functional teams within the TS&EM department and across Early CVRM to establish project-specific clinical research strategies and translational science plans for compounds targeting CV, metabolic and renal diseases. You will be a member of the TS&EM leadership team. Additional accountabilities include: