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Senior Scientist, Analytical Sciences- Biopharmaceutical Dev
Job description
Our Cambridge (UK) facility creates life-changing medicines for people around the world. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We believe employees benefit from being challenged and inspired at work. We are dedicated to creating a culture of inclusion and collaboration. Summary of the group:In the Analytical Sciences – Physicochemical Development teams we enable the advancement of AZ’s biologics and new modalities portfolio using industry-leading analytical technologies. We are responsible for establishing platform methodologies and analytical strategies capable of supporting the pharmaceutical development of diversified modalities, that will become life-changing medicines. Main Duties & Responsibilities:We are seeking a skilled and highly motivated Senior Scientist to join the Analytical Sciences – Physicochemical Development team in Cambridge, to work on Protein- and RNA-based therapeutics. The successful candidates will:be responsible for the development of analytical capabilities for biotherapeutics that will support the product development from early stages through to clinical studies (including establishment or development of new technologies and/or methods)be responsible for advancing our understanding of these molecules to ensure the appropriate Critical Quality Attributes are being monitored and managedwork in close collaboration with other teams, including those responsible for the process development, molecule design/engineering and product quality, as well as external collaborators and CMOs, to ensure efficient progress of the project(s)
Responsibilities & skills
Education
Knowledge of global regulatory frameworks and guidelines (e.g., FDA, EMA, ICH)Highly motivated, proactive individual with strong scientific curiosity and interest in continued learning. Team player with confidence to work with independently.
Experience
Practical experience with the principles and concepts associated with the analysis and characterization of both protein- and nucleic acid-based therapeutics as well as with GLP/GMP production environmentPractical experience with electrophoresis- and liquid chromatography-based methodsExperience with Mass spectrometry-based methods and method development
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AstraZeneca Uk
A global pharmaceutical company with a major UK presence. Our purpose is to push the boundaries of science to deliver life-changing medicines. The best way we can help patients is to be science-led and share this passion with the scientific, healthcare and business communities of the UK.
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