Job description
methods that enhance target discovery and early-stage drug development. This position is part of Bayer's Life ScienceCollaboration program, which fosters cutting-edge research across the global Bayer organization, with a particular emphasis oncross-divisional collaboration. In this role, you will establish a high throughput platform to perform proximity based interactomeanalysis using novel enzymes engineered in-house, working closely with colleagues from Crop Science and Pharma in both Europeand the US. Imaging & Omics cluster (CBIO) within Drug Discovery Sciences (DDS) in Germany. In this role at CBIO, you will collaborate withan interdisciplinary team of scientists within the R&D organization, contributing to the development and discovery of innovativemethods that enhance target discovery and early-stage drug development. This position is part of Bayer's Life ScienceCollaboration program, which fosters cutting-edge research across the global Bayer organization, with a particular emphasis oncross-divisional collaboration. In this role, you will establish a high throughput platform to perform proximity based interactomeanalysis using novel enzymes engineered in-house, working closely with colleagues from Crop Science and Pharma in both Europeand the US. YOUR TASKS AND RESPONSIBILITIES You establish a fully automated enrichment platform for protein interactome studiesYou design, implement, and optimize experimental workflows for proximity labeling experimentsYou develop and refine fusion constructs and generate stable cell linesYou collaborate with the protein engineering team to create novel proximity labeling enzymesYou perform proteomics/mass spectrometry experiments, from sample preparation to data acquisitionYou closely collaborate with data scientists and computational biologists to ensure quantitative analysis of generated data and identify novel protein-protein interactionsYou support ongoing drug discovery projects at various stages, including target discovery, target deconvolution, and lead characterization activities with this platformYou join a highly motivated, international, and interdisciplinary research team, closely interacting with your colleagues from the entire R&D organization of Bayer Pharma, as well as several contract research organizations You establish a fully automated enrichment platform for protein interactome studiesYou design, implement, and optimize experimental workflows for proximity labeling experimentsYou develop and refine fusion constructs and generate stable cell linesYou collaborate with the protein engineering team to create novel proximity labeling enzymesYou perform proteomics/mass spectrometry experiments, from sample preparation to data acquisitionYou closely collaborate with data scientists and computational biologists to ensure quantitative analysis of generated data and identify novel protein-protein interactions
Responsibilities & skills
We support your professional growth by providing access to learning and development opportunities, training programs through the Bayer Learning Academy, development dialogues, as well as coaching and mentoring programs.We promote health awareness and opportunities for selfcare through various measures, such as free health checks with the company doctor and our health platform #machfit.
Education
Whether its hybrid work models or part-time arrangements: Whenever it is possible, you will have the flexibility to work how, when and where it is best for you.Your family is a top priority. We offer loving company daycare centers at multiple locations, support in finding childcare, time off for the care of elderly or dependent family members, summer camps for children, and much more.
Experience
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