Co-funded by the ANR (French National Research Agency) and the DFG (German Research Foundation), our project investigates how the communication between the endoplasmic reticulum and mitochondria, at contact sites called mitochondria-associated membranes (MAMs), influences development and recovery from metabolic dysfunction-associated steatotic liver disease (MASLD; formerly NAFLD). Our project spans in vitro approaches (in both hepatocytes and non-parenchymal cells), in vivo modelling (in mice) and a clinical trial. These are coordinated over 4 partner labs in Paris, Lyon, Munich and Lisbon. We seek to recruit 3 postdocs and 1 technical staff; each position will be based at a partner lab and will require extensive coordination and cooperation with other partner labs. 

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